DNACINS, NEW ANTIBIOTICS

II. ISOLATION AND CHARACTERIZATION

Abstract

Dnacins A₁and B₁, new basic antibiotics with strong and broad antibacterial activities, were isolated as dark red or reddish brown needles from the culture broth of Nocardia sp. No. C-14482. The characteristic absorption maxima at 213 nm, 281 or 283 nm and 496 nm in the UV and visible range and other physicochemical properties indicated that dnacins A₁ and B₁ are novel antibiotics which belong to the group having aminobenzoquinone moieties.