1981 Volume 34 Issue 12 Pages 1569-1576
Pyrrolomycin A, a new antifungal antibiotic produced by an actinomycete, has a molecular formula C4H2N202Cl2. Its structure was determined to be 2, 3-dichloro-4-nitropyrrole by spectroscopic analysis and synthetic studies. Structure-activity relationships among the analogs of pyrrolomycin A are discussed.