EM5400, A FAMILY OF MONOBACTAM ANTIBIOTICS PRODUCED BY AGROBACTERIUM RADIOBACTER I. TAXONOMY, FERMENTATION AND BIOLOGICAL PROPERTIES

J. SCOTT WELLS; WILLIAM H. TREJO; PACIFICO A. PRINCIPE; KAREN BUSH; NAFSIKA GEORGOPAPADAKOU; DANIEL P. BONNER; RICHARD B. SYKES

doi:10.7164/antibiotics.35.295

EM5400, A FAMILY OF MONOBACTAM ANTIBIOTICS PRODUCED BY AGROBACTERIUM RADIOBACTER

I. TAXONOMY, FERMENTATION AND BIOLOGICAL PROPERTIES

J. SCOTT WELLS, WILLIAM H. TREJO, PACIFICO A. PRINCIPE, KAREN BUSH, NAFSIKA GEORGOPAPADAKOU, DANIEL P. BONNER, RICHARD B. SYKES

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JOURNAL FREE ACCESS

1982 Volume 35 Issue 3 Pages 295-299

DOI https://doi.org/10.7164/antibiotics.35.295

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Abstract

A series of novel monocyclic β-lactam antibiotics were isolated from a strain of Agrobacterium radiobacter. The compounds show weak antibacterial activity but are highly stable to hydrolysis by β-lactamases.

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