CERVINOMYCIN A1 AND A2, NEW ANTIBIOTICS ACTIVE AGAINST ANAEROBES, PRODUCED BY STREPTOMYCES CERVINUS SP. NOV.

SATOSHI OMURA; YUZURU IWAI; KIYOIZUMI HINOTOZAWA; YOKO TAKAHASHI; JUNKO KATO; AKIRA NAKAGAWA; ATSUSHI HIRANO; HIDEKI SHIMIZU; KATSUJI HANEDA

doi:10.7164/antibiotics.35.645

CERVINOMYCIN A₁ AND A₂, NEW ANTIBIOTICS ACTIVE AGAINST ANAEROBES, PRODUCED BY STREPTOMYCES CERVINUS SP. NOV.

SATOSHI OMURA, YUZURU IWAI, KIYOIZUMI HINOTOZAWA, YOKO TAKAHASHI, JUNKO KATO, AKIRA NAKAGAWA, ATSUSHI HIRANO, HIDEKI SHIMIZU, KATSUJI HANEDA

Author information

SATOSHI OMURA
The Kitasato Institute and Kitasato University
YUZURU IWAI
The Kitasato Institute and Kitasato University
KIYOIZUMI HINOTOZAWA
The Kitasato Institute and Kitasato University
YOKO TAKAHASHI
The Kitasato Institute and Kitasato University
JUNKO KATO
The Kitasato Institute and Kitasato University
AKIRA NAKAGAWA
The Kitasato Institute and Kitasato University
ATSUSHI HIRANO
Food and Fine Chemical Plant, Asahi Chemical Industry Co. Ltd.
HIDEKI SHIMIZU
Food and Fine Chemical Plant, Asahi Chemical Industry Co. Ltd.
KATSUJI HANEDA
Food and Fine Chemical Plant, Asahi Chemical Industry Co. Ltd.

JOURNAL FREE ACCESS

1982 Volume 35 Issue 6 Pages 645-652

DOI https://doi.org/10.7164/antibiotics.35.645

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Abstract

Two new antibiotics, cervinomycin A₁ and A₂, were isolated from the culture filtrate of strain AM-5344, a soil isolate. The strain was found to belong to a new species of the genus Streptomyces for which the name Streptomyces cervinus is proposed. The antibiotics possess a strong inhibitory activity against anaerobic bacteria, such as Clostridium perfringens, Peptococcus prevotii and Bacteroides fragilis.

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