SQ 27, 860, A SIMPLE CARBAPENEM PRODUCED BY SPECIES OF SERRATIA AND ERWINIA

Abstract

In our continued search for the production of β-lactam-containing molecules from bacteria, we report the isolation and structure determination of a simple carbapenem SQ 27, 860, produced by species of Serratia and Erwinia. The antibiotic is highly unstable and isolation was achieved through the p-nitrobenzyl ester.