GLYCOCINNAMOYLSPERMIDINES, A NEW CLASS OF ANTIBIOTICS VI. PREPARATION AND CHARACTERIZATION OF THE SEMISYNTHETIC IPROCINODINE

W. J. MCGAHREN; F. BARBATSCHI; N. A. KUCK; G. O. MORTON; B. HARDY; G. A. ELLESTAD

doi:10.7164/antibiotics.35.794

GLYCOCINNAMOYLSPERMIDINES, A NEW CLASS OF ANTIBIOTICS

VI. PREPARATION AND CHARACTERIZATION OF THE SEMISYNTHETIC IPROCINODINE

W. J. MCGAHREN, F. BARBATSCHI, N. A. KUCK, G. O. MORTON, B. HARDY, G. A. ELLESTAD

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JOURNAL FREE ACCESS

1982 Volume 35 Issue 7 Pages 794-799

DOI https://doi.org/10.7164/antibiotics.35.794

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Abstract

Conditions for the preparation and purification of iprocinodine are described. This material is the isopropylated derivative of active glycocinnamoylspermidine metabolites of a Nocardia species. The resolution and characterization of minor components generated during the chemical reaction are also outlined.

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