The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
FERENSIMYCINS A AND B, TWO POLYETHER ANTIBIOTICS
TAXONOMY, FERMENTATION, ISOLATION, CHARACTERIZATION AND STRUCTURAL STUDIES
YOKO KUSAKABETAKU MIZUNOSHOZO KAWABATASHOJI TANJIAKIO SEINOHARUO SETONOBORU TAKE
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1982 Volume 35 Issue 9 Pages 1119-1129

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Abstract

Ferensimycin A* (I), C34H59O10Na, mp 133-135°C, and ferensimycin B** (II), C35H61O10Na, mp 143-145°C, were isolated as their sodium salts from the fermentation broth of Streptomyces sp. No. 5057, a strain similar to Streptomyces myxogenes Shomura et al. The physicochemical data of I and II showed that they are both closely related congeners of lysocellin (III). Ferensimycins A and B exhibit activity against Gram-positive bacteria and are effective in the treatment of coccidiosis of fowl.

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© Japan Antibiotics Research Association
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