NEW POLYENIC ANTIBIOTICS ACTIVE AGAINST GRAM-POSITIVE AND -NEGATIVE BACTERIA

I. ISOLATION AND PURIFICATION OF ANTIBIOTICS PRODUCED BY GLUCONOBACTER SP. W-315

Abstract

A new antibiotic, tentatively named as AB-315, was isolated from the fermentation broth of Gluconobacter sp. W-315. The antibiotic consists of a mixture of chemically related compounds. These compounds showed similar profiles in UV absorbancy. The antibiotics were active against Gram-positive and -negative bacteria, slightly active against fungi but not against yeasts.