ISOLATION AND CHARACTERIZATION OF ANCOVENIN, A NEW INHIBITOR OF ANGIOTENSIN I CONVERTING ENZYME, PRODUCED BY ACTINOMYCETES

Abstract

Ancovenin, an inhibitor of angiotensin I converting enzyme isolated from the culture broth of a Streptomyces species, is a dialysable peptide composed of sixteen amino acid residues containing unusual amino acids such as threo-β-methyllanthionine, meso-lanthionine, and dehydroalanine.