The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
THE PREPARATION AND DETERMINATION OF STRUCTURE OF BENZYLPENICILLOYL COMPOUNDS USED IN SKIN-TESTING FOR PENICILLIN ALLERGY
BERNARD M. GOLDSCHMIDTBERNARD B. LEVINE
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1983 Volume 36 Issue 6 Pages 709-714

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Abstract

The preparation of α-D-benzylpenicilloyl-n-propylamine and octa-ε-(α-D-benzylpenicilloyl)-octa-α-L-lysine are described. Their structures were established by chemical and spectroscopic evidence. Proton and carbon-13 nuclear magnetic resonance spectra of these two penicillin derivatives and some related compounds are provided. These compounds are useful in skin testing for penicillin allergy.

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© Japan Antibiotics Research Association
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