The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
PHENACEIN-AN ANGIOTENSIN-CONVERTING ENZYME INHIBITOR PRODUCED BY A STREPTOMYCETE
II. ISOLATION, STRUCTURE DETERMINATION AND SYNTHESIS
WEN-CHIH LIU, WILLIAM L. PARKER, STEVEN S. BRANDT, KARNAIL S. ATWAL, ERIC P. RUBY
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1984 Volume 37 Issue 11 Pages 1313-1319

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Abstract
Phenacein, an inhibitor of angiotensin-converting enzyme, has been isolated from the fermentation broth of a Streptomyces species belonging to the Streptomyces tanashiensiszaomyceticus group. The inhibitor was shown to be 3, 6-dihydroxy-1-phenazinecarboxylic acid by spectroscopic, degradative and synthetic methods.
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© Japan Antibiotics Research Association
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The Journal of Antibiotics, Series A

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