The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
CHLOROCARDICIN, A MONOCYCLIC β-LACTAM FROM A STREPTOMYCES SP.
II. ISOLATION, PHYSICO-CHEMICAL PROPERTIES AND STRUCTURE DETERMINATION
JAMES A. CHANELVA A. SHULTISJOHN J. DINGERDISSENCHARLES W. DEBROSSEGERALD D. ROBERTSKENNETH M. SNADER
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1985 Volume 38 Issue 2 Pages 139-144

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Abstract

Chlorocardicin, a novel monocyclic β-lactam, was isolated from the fermentation broth of a Streptomyces sp. by the use of non-ionic porous resin and reverse phase chromatography. This chlorine-containing antibiotic is structurally related to nocardicin A. Its physico-chemical characteristics and detailed NMR analysis are described.

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© Japan Antibiotics Research Association
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