The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
THE STRUCTURE OF AMPHOTERICIN A
II. THE COMPLETE STRUCTURE OF THE ANTIBIOTIC
PAWEL SOWINSKIJAN K. PAWLAKEDWARD BOROWSKITAKASHI IWASHITA
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JOURNAL FREE ACCESS

1985 Volume 38 Issue 2 Pages 175-180

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Abstract

The structure of amphotericin A without the configuration of asymmetric carbon atoms has been elucidated. The stereochemistry of the sugar moiety has been determined. On the basis of homoscalar correlated 2D 1H spectra of amphotericin A the position of the hemiketal moiety has been located, and the chemical shifts of all the protons in the antibiotic molecule have been determined.

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© Japan Antibiotics Research Association
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