The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
INCLUSION COMPOUNDS OF LANKACIDIN-GROUP ANTIBIOTICS WITH CYCLODEXTRINS
SETSUO HARADAJUNYA OKADAMASUO TAKEDATOSHIYUKI YAMAZAKI
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1985 Volume 38 Issue 7 Pages 877-885

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Abstract
Lankacidin-group antibiotics formed inclusion compounds with β-cyclodextrin in molar ratios of about 1:1. These compounds showed remarkably improved water-solubility and stability in aqueous solutions. The structure of the inclusion compounds of lankacidin A is proposed based on the facility of their inclusion with β-cyclodextrin and the results of 1H NMR spectral studies.
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© Japan Antibiotics Research Association
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