DC-86-M, A NOVEL ANTITUMOR ANTIBIOTIC

II. STRUCTURE DETERMINATION AND BIOLOGICAL ACTIVITIES

Abstract

A novel antibiotic, DC-86-M was isolated from the culture broth of Streptomyces luteogriseus DO-86. The antibiotic has the molecular formula of C₁₇H₁₄N₂O₅ and belongs to the phenazine antibiotics. Its structure has been elucidated by mass and NMR spectra. It is active against Gram-positive and Gram-negative bacteria and experimental murine sarcoma 180.