UK-69, 753, A NOVEL MEMBER OF THE EFROTOMYCIN FAMILY OF ANTIBIOTICS I. TAXONOMY OF THE PRODUCING ORGANISM, FERMENTATION AND ISOLATION

MICHAEL S. PACEY; MARTIN R. JEFSON; LIANG H. HUANG; WALTER P. CULLEN; HIROSHI MAEDA; JUNSUKE TONE; SATOSHI NISHIYAMA; KEIJI KANEDA; MASARU ISHIGURO

doi:10.7164/antibiotics.42.1453

UK-69, 753, A NOVEL MEMBER OF THE EFROTOMYCIN FAMILY OF ANTIBIOTICS

I. TAXONOMY OF THE PRODUCING ORGANISM, FERMENTATION AND ISOLATION

MICHAEL S. PACEY, MARTIN R. JEFSON, LIANG H. HUANG, WALTER P. CULLEN, HIROSHI MAEDA, JUNSUKE TONE, SATOSHI NISHIYAMA, KEIJI KANEDA, MASARU ISHIGURO

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JOURNAL FREE ACCESS

1989 Volume 42 Issue 10 Pages 1453-1459

DOI https://doi.org/10.7164/antibiotics.42.1453

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Abstract

UK-69, 753 is a novel antibiotic structurally related to efrotomycin and factumycin, produced by a new strain of Amycolatopsis orientalis (ATCC 53550). The antibiotic potency in the fermentation broth was monitored by HPLC with diode array detection. A six tube counter current distribution was used to purify UK-69, 753.

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