LL-E19020α AND β, ANIMAL GROWTH PROMOTING ANTIBIOTICS: TAXONOMY, FERMENTATION AND BIOLOGICAL ACTIVITY

W. M. MAIESE; M. P. LECHEVALIER; H. A. LECHEVALIER; J. KORSHALLA; J. GOODMAN; M. J. WILDEY; N. KUCK; S. D. CONNER; M. GREENSTEIN

doi:10.7164/antibiotics.42.1489

W. M. MAIESE, M. P. LECHEVALIER, H. A. LECHEVALIER, J. KORSHALLA, J. GOODMAN, M. J. WILDEY, N. KUCK, S. D. CONNER, M. GREENSTEIN

Author information

W. M. MAIESE
Medical Research Division, American Cyanamid Company, Lederle Laboratories
M. P. LECHEVALIER
Rutgers University
H. A. LECHEVALIER
Rutgers University
J. KORSHALLA
Medical Research Division, American Cyanamid Company, Lederle Laboratories
J. GOODMAN
Medical Research Division, American Cyanamid Company, Lederle Laboratories
M. J. WILDEY
Medical Research Division, American Cyanamid Company, Lederle Laboratories
N. KUCK
Medical Research Division, American Cyanamid Company, Lederle Laboratories
S. D. CONNER
Agricultural Research Division, American Cyanamid Company
M. GREENSTEIN
Medical Research Division, American Cyanamid Company, Lederle Laboratories

JOURNAL FREE ACCESS

1989 Volume 42 Issue 10 Pages 1489-1493

DOI https://doi.org/10.7164/antibiotics.42.1489

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Abstract

Antibacterial antibiotics LL-E19020α and β were isolated from the fermentation broth of an actinomycete strain. Based on cultural and physiological characteristics, culture LL-E19020 was identified as a new subspecies of Streptomyces lydicus. The LL-E19020α and β antibiotics were found to possess a very narrow antibacterial spectrum against human pathogens. In studies in chickens, LL-E19020α demonstrated excellent growth promoting activity.

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