The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
PACIDAMYCINS, A NOVEL SERIES OF ANTIBIOTICS WITH ANJI-PSEUDOMONAS AERUGINOSA ACTIVITY
II. ISOLATION AND STRUCTURAL ELUCIDATION
RANDAL H. CHENALEXANDER M. BUKODAVID N. WHITTERNJAMES B. MCALPINE
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1989 Volume 42 Issue 4 Pages 512-520

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Abstract

A novel class of antibiotics was isolated from cultures of Streptomyces coeruleorubidus strain AB 1183F-64. The antimicrobial activity of the pacidamycins is selective against Pseudomonas aeruginosa. The various congeners are nucleoside peptides which differ in the terminal amino acid residues. The structures were determined using MS-MS and 2D NMR techniques.

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© Japan Antibiotics Research Association
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