COUMAMIDINES, NEW BROAD SPECTRUM ANTIBIOTICS OF THE CINODINE TYPE I. DISCOVERY, TAXONOMY OF THE PRODUCING ORGANISM AND FERMENTATION

MARIANNA JACKSON; JAMES P. KARWOWSKI; ROBERT J. THERIAULT; WILLIAM L. KOHL; PATRICK E. HUMPHREY; GABRIELA N. SUNGA; SUE J. SWANSON; ROSITA M. VILLARREAL

doi:10.7164/antibiotics.42.527

COUMAMIDINES, NEW BROAD SPECTRUM ANTIBIOTICS OF THE CINODINE TYPE

I. DISCOVERY, TAXONOMY OF THE PRODUCING ORGANISM AND FERMENTATION

MARIANNA JACKSON, JAMES P. KARWOWSKI, ROBERT J. THERIAULT, WILLIAM L. KOHL, PATRICK E. HUMPHREY, GABRIELA N. SUNGA, SUE J. SWANSON, ROSITA M. VILLARREAL

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JOURNAL FREE ACCESS

1989 Volume 42 Issue 4 Pages 527-532

DOI https://doi.org/10.7164/antibiotics.42.527

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Abstract

Coumamidines are water-soluble basic antibiotics related to the glycocinnamoylspermidines. They are produced by a soil isolate designated Saccharopolyspora sp. AB 1167L-65. The coumamidines have broad spectrum activity and were selected in a screen for substances which inhibit Pseudomonas aeruginosa.

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