COUMAMIDINES, NEW BROAD SPECTRUM ANTIBIOTICS OF THE CINODINE TYPE

II. ISOLATION AND STRUCTURAL ELUCIDATION

Abstract

Two novel, isomeric compounds, coumamidines γl and γ2 were isolated from fermentations of an actinomycete. The structures were elucidated spectroscopically using 2D NMR correlation experiments and mass spectral data. The coumamidines were found to be close structural relatives of the cinodines (LL-BM123 γl and γ2).