1989 Volume 42 Issue 5 Pages 691-700
A new insecticidal antibiotic, aculeximycin (ACM), was produced by an actinomycete identified as Streptosporangium albidum. ACM has been successfully isolated from culture filtrate by a combination of Diaion HP-20, Amberlite CG-50, reversed phase silica gel and Sephadex LH-20 chromatographies. It was found that ACM is a basic glycosidic antibiotic with a molecular weight of 1, 672 including five monosaccharide units, three double bonds and a hemiketal ring by preliminary spectral analyses.
Treatment of ACM with l, 8-diazabicyclo[5, 4, 0]undecene-7 caused a glycosidic bond cleavage to give aculexitriose, pseudoaglycones I and II.