The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ANTIBIOTICS FROM BASIDIOMYCETES
XXXI. ALEURODISCAL: AN ANTIFUNGAL SESTERTERPENOID FROM ALEURODISCUS MIRABILIS (BERK. & CURT.) HÖHN.
URSULA LAUERTIMM ANKEWILLIAM S. SHELDRICKANGELA SCHERERWOLFGANG STEGLICH
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1989 Volume 42 Issue 6 Pages 875-882

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Abstract

Aleurodiscal, an antifungal antibiotic has been isolated from mycelial cultures of Aleurodiscus mirabilis (Berk. & Curt.) Höhn. It causes abnormal apical branchings of Mucor miehei hyphae at very low concentrations. The structure and absolute configuration of the antibiotic has been determined by a single crystal X-ray analysis and hydrolysis to D-(+)-xylose. Aleurodiscal is a hydroxysesterterpene aldehyde β-D-xyloside with a novel carbon skeleton.

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