The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
FR109615, A NEW ANTIFUNGAL ANTIBIOTIC FROM STREPTOMYCES SETONII
TAXONOMY, FERMENTATION, ISOLATION, PHYSICO-CHEMICAL PROPERTIES AND BIOLOGICAL ACTIVITY
TOSHIRO IWAMOTO, EISAKU TSUJII, MASAMI EZAKI, AKIHIKO FUJIE, SEIJI HASHIMOTO, MASAKUNI OKUHARA, MASANOBU KOHSAKA, HIROSHI IMANAKA, KOHJI KAWABATA, YOSHIKO INAMOTO, KAZUO SAKANE
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1990 Volume 43 Issue 1 Pages 1-7

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Abstract

FR109615, a new antibiotic active against Candida, was isolated from Streptomyces setonii No. 7562. Based on the spectroscopic data, the structure of FR109615 was elucidated as cis-2-aminocyclopentane-1-carboxylic acid (1). The compound showed the excellent in vivo efficacy in a generalized infection test of mice.

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© Japan Antibiotics Research Association
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The Journal of Antibiotics, Series A

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