The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ANTIBIOTICS FROM BASIDIOMYCETES
XXXII. STROBILURIN E: A NEW CYTOSTATIC AND ANTIFUNGAL (E)-β-METHOXYACRYLATE ANTIBIOTIC FROM CREPIDOTUS FULVOTOMENTOSUS PECK
WOLFGANG WEBERTIMM ANKEBERT STEFFANWOLFGANG STEGLICH
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1990 Volume 43 Issue 2 Pages 207-212

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Abstract

Strobilurin E is a novel antibiotic of the (E)-β-methoxyacrylate (MOA) class produced by mycelial cultures of the agaric Crepidotus fulvotomentosus. In addition to an inhibition of fungal respiration, a feature of all MOA-antibiotics, the compound exhibits very high cytostatic activities which are accompanied by reversible morphological alterations of the cells.

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© Japan Antibiotics Research Association
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