The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
HYDRAMYCIN, A NEW ANTITUMOR ANTIBIOTIC
TAXONOMY, ISOLATION, PHYSICO-CHEMICAL PROPERTIES, STRUCTURE AND BIOLOGICAL ACTIVITY
MINORU HANADA, KEIKO KANETA, YUJI NISHIYAMA, YUTAKA HOSHINO, MASATAKA KONISHI, TOSHIKAZU OKI
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1991 Volume 44 Issue 8 Pages 824-831

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Abstract

A new antitumor antibiotic hydramycin was isolated from the fermentation broth of Streptomyces violaceus P950-4 (ATCC 53807). It showed potent antibacterial and cytotoxic activity and increased the survival time of mice inoculated with P388 leukemia. A new structure related to the pluramycin group antibiotics was assigned by its spectroscopic experiments.

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© Japan Antibiotics Research Association
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The Journal of Antibiotics, Series A

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