BENARTHIN: A NEW INHIBITOR OF PYROGLUTAMYL PEPTIDASE

II. PHYSICO-CHEMICAL PROPERTIES AND STRUCTURE DETERMINATION

Abstract

Benarthin, a new inhibitor of pyroglutamyl peptidase (PG-peptidase), has been isolated from the culture broth of Streptomyces xanthophaeus MJ244-SF1. The structure of benarthin was determined to be L-(2, 3-dihydroxybenzoyl)argininyl-L-threonine by analysis of spectral properties and through chemical studies.