YM-47141 and YM-47142, New Elastase Inhibitors Produced by Flexibacter sp. Q17897 II. Structure Elucidation

MASAYA ORITA; KENICHI YASUMURO; KUNIHIKO KOKUBO; MINORU SHIMIZU; KENJI ABE; TATSUHIRO TOKUNAGA; HIDETOSHI KANIWA

doi:10.7164/antibiotics.48.1430

YM-47141 and YM-47142, New Elastase Inhibitors Produced by Flexibacter sp. Q17897

II. Structure Elucidation

MASAYA ORITA, KENICHI YASUMURO, KUNIHIKO KOKUBO, MINORU SHIMIZU, KENJI ABE, TATSUHIRO TOKUNAGA, HIDETOSHI KANIWA

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JOURNAL FREE ACCESS

1995 Volume 48 Issue 12 Pages 1430-1434

DOI https://doi.org/10.7164/antibiotics.48.1430

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Abstract

YM-47141 and YM-47142 are new elastase inhibitor produced by Flexibacter sp. Q17897. These structures were elucidated by MS and NMR spectral analysis. YM-47141 and YM-47142 were the cyclic pep tides containing tricarbonyl moiety hydrated on the center carbonyl carbon in DMSO-d₆.

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