A Novel Bioactive δ lactone FD-211

OSAMU NOZAWA; TADAYASU OKAZAKI; NORIYOSHI SAKAI; TOSHI KOMURASAKI; KAZUNORI HANADA; SHIGEO MORIMOTO; ZENG-XIANG CHEN; BI-MEI HE; KAZUTOSHI MIZOUE

doi:10.7164/antibiotics.48.113

Taxonomy, Isolation and Characterization

OSAMU NOZAWA, TADAYASU OKAZAKI, NORIYOSHI SAKAI, TOSHI KOMURASAKI, KAZUNORI HANADA, SHIGEO MORIMOTO, ZENG-XIANG CHEN, BI-MEI HE, KAZUTOSHI MIZOUE

Author information

JOURNALS FREE ACCESS

Volume 48 (1995) Issue 2 Pages 113-118

DOI https://doi.org/10.7164/antibiotics.48.113

Details

Abstract

During our screening program for natural product drugs effective against multidrug-resistant mammalian cells, we have discovered a new δ lactone FD-211 from the fermantation broth of Myceliophthora lutea TF-0409. FD-211 had a broad spectrum activity against cultured tumor cell lines, including adriamycin-resistant HL-60 cells.

Released dates

Register with J-STAGE for free!