2000 Volume 53 Issue 11 Pages 1252-1256
Three novel quinolone compounds, quinolactacins A (1), B (2) and C (3), Have been found from the fermentation broth of Penidllium sp. EPF-6, a fungus isolated from the larvae of mulberry pyralid (Margaronia pyloalis Welker). The molecular formulas of 1, 2 and 3 were determined to be C16H18N2O2, C15H16N2O2 and C16H18N2O3, respectively by FAB-MS and NMR spectral analyses. The structures of these compounds have a novel quinolone skeleton with a γ-lactam ring consisting of C12H8N2O2 as the common chromophore.