The Journal of Antibiotics
Tripropeptins, Novel Antimicrobial Agents Produced by Lysobacter sp.
I. Taxonomy, Isolation and Biological Activities
HIDEKI HASHIZUMEMASAYUKI IGARASHISEIKO HATTORIMAKOTO HORIMASA HAMADATOMIO TAKEUCHI
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Volume 54 (2001) Issue 12 Pages 1054-1059

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Abstract

Peptide antibiotics tripropeptins A, B, C, D and Z were isolated from cultured cells and broth of Lysobacter sp. The differences among these components are in the lengths of the alkyl side chain. Tripropeptins are active against Gram-positive bacteria including MRSA in vitro. Bactericidal activity of tripropeptin C disappeared in the simultaneous presence of chloramphenicol, a bacteriostatic agent.

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