Deacetylravidomycin M, a New Inhibitor of IL-4 Signal Transduction, Produced by Streptomyces sp. WK-6326

II. Structure Elucidation

Abstract

The structure of deacetylravidomycin M, an inhibitor of interleukin-4 signal transduction, was elucidated to be 6H-benzo[d]naphtho[l, 2-b]pyran-6-one, 4-[3, 6-dideoxy-3-(dimethylamino)-α-altropyranosyl]-l-hydroxy-10, 12-dimethoxy-8-methyl- by spectroscopic studies including NMR measurements.