The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
A Novel Antibiotic CJ-17, 572 from a Fungus, Pezicula sp.
YUTAKA SUGIEKOEN A. DEKKERTAISUKE INAGAKIYOON-JEONG KIMTATSUO SAKAKIBARASHINICHI SAKEMIAKEMI SUGIURALORI BRENNANJOAN DUIGNANJOYCE A. SUTCLIFFEYASUHIRO KOJIMA
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2002 Volume 55 Issue 1 Pages 19-24

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Abstract

A new antibiotic, CJ-17, 572 (I) was isolated from the fermentation broth of a fungus Pezicula sp. CL11877. The structure of I was determined to be a new equisetin derivative by spectroscopic analyses. The compound inhibits the growth of multi-drug resistant Staphylococcus aureus and Enterococcus faecalis with IC50s of 10 and 20μg/ml, respectively.

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