Parimycin: Isolation and Structure Elucidation of a Novel Cytotoxic 2, 3-Dihydroquinizarin Analogue of γ-Indomycinone from a Marine Streptomycete Isolate

Abstract

In our screening of actinomycetes from the marine environment for bioactive components, a new antibiotic with a novel structure designated as parimycin was obtained from the culture broth of Streptomyces sp. isolate B8652. The structure of the new antibiotic was determined by spectroscopic methods and by comparison of the NMR data with those of the structurally related γ-indomycinone.