The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
IB-00208, a New Cytotoxic Polycyclic Xanthone Produced by a Marine-derived Actinomadura
I. Isolation of the Strain, Taxonomy and Biological Activites
LEYRE MALET-CASCÓNFRANCISCO ROMEROFERNANDO ESPLIEGO-VÁZQUEZDOLORES GRÁVALOSJOSÉ LUIS FERNÁNDEZ-PUENTES
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2003 Volume 56 Issue 3 Pages 219-225

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Abstract

A new compound, IB-00208, has been isolated from the fermentation broth of an actinomycete isolated from a marine environment. The strain was identified as Actinomadura sp. by its chemical and phylogenetic characteristics. The compound shows cytotoxic activity on tumor cell lines and bactericidal activity against Gram-positive bacteria.

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