1958 Volume 11 Issue 3 Pages 109-115
In the preceding communications of this series1,2,3), it was reported that the high level demand of oxygen was perceived in the young cells (24-hour cultured cells) of Streptomyces griseus grown on soybean and casein media. But the metabolic pathway of the young cells has not been cleared as yet. Cochran4), Hockenhull5), Gilmour6), and Youmas7) demonstrated with Streptomyces coelicolor, Streptomyces griseus, and tubercule bacteria that these microorgamisms oxidized various intermediates of the Krebs tricarboxylic acid cycle. Evidence for and against the active participation of various terminal pathways in microbial metabolism has been reviewed by Ajl8).
The purpose of the present study is to clarify the rôle of these terminal pathways in the metabolism of the young cells of S. griseus, with special reference to the Krebs cycle.