The Therapeutic Effect of Variotin, A New Antifungal Antibiotic, on Tinea Pedis and Tinea Cruris

Abstract

Variotin is a faintly yellowish, oily antibiotic isolated at the Institute of Applied Microbiology, Tokyo University from Paecilomyces varioti Bainier var. antibioticus. It is insoluble in water, but soluble in various organic solvents. Recent studies on variotin have shown the favorable antifungal activity against pathogenic fungi of ringworm. The present paper describes the observation on the effectiveness of variotin topical treatment in the patients with dermatomycoses.