The Effects of Variotin on Dermatomycosis. II On the Relation Between Therapeutic Results and Detection of Fungi After Treatment

Abstract

The therapeutic results of dermatomycosis with antifungal agent, variotin, has teen published by the present authors. At that time, variotin was smeared topically 2–3 times a day with brush. The effect was remarkable in 20 cases, effective in 10, ineffective in 12 out of 46, and effective rate was 76%. Clinically, variotin was characterized in its low irritability. Slight irritation was experienced only in 2 out of 46 cases of wet type of trichophytia pompholyciformis. However, smearing variotin directly to 7 wet type cases caused less irritation as compared with usual mercuric preparations. This may due to oiliness of variotin. In addition, it is of interest that variotin was remarkably effective of trichophytia interdigitalis, as reported by Tanuma.