The Journal of Antibiotics, Series A
Online ISSN : 2435-5135
Print ISSN : 0368-1173
ISSN-L : 0368-1173
Original articles
Treatment of Dermatomycoses with Griseofulvin
Ryoichi FukushiroSaburō KagawaHisashi Takahashi
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1960 Volume 13 Issue 3 Pages 204-210

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Abstract

Griseofulvin is an antibiotic first isolated by 0xford, Raistick and Simonart.1) Its chemical structure was clarified by Grove, MacMillan, Mulholland and Rogers.2) Formerly this substance was applied as a curative agent for fungus diseases in plants,3) but in 1958 Gentles4) proved its effectiveness in experimental ringworm of guinea pigs when given orally. This investigation led its usage for dermatomycoses in man and a number of cases have been reported5–9) since then.

In this paper are reported the results obtained m 29 cases of clermatomycosis treated with griseofulvin.

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© 1960 JAPAN ANTIBIOTICS RESEARCH ASSOCIATION
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