In order to find the state of sensitization to various antigens for adult bronchial asthma in Nagasaki prefecture located in western Japan, we investigatied the results of the intradermal test, threshold of the intradermal test, Prausnitz-Kustner reaction, and bronchial provocation test. The investigation included 613 asthamtic subjects using 59 allergens over a priod of 9 years (1975-1983). 1) House dust was the primary allergen in Nagasaki prefecture. Candida was the second most important allergen and Boehameria nivea third. 2) Boehemeria nivea was regarded as the most improtant of the pollen allergens in Nagasaki prefecture. 3) Rates of positive reactions for the intradermal test for a period of 9 years indicated increases for ragweed, no change for house dust and decreases for molds and barley straw. 4) Comparing positive test reaction rates between Nagasaki and published test results from other districts, Nagasaki was lower than Shizuoka and Kyoto and higher than sagamihara for house dust; lower then Niigata, Shizuoka and Tokyo for molds and about equal to Sagamihara and Kyoto for molds; and lower than Sagamihara for pollens, especially cedar pollen.
