Effects of Dietary myo-Inositol, <small>D</small>-chiro-Inositol and <small>L</small>-chiro-Inositol on Hepatic Lipids with Reference to the Hepatic myo-Inositol Status in Rats Fed on 1,1,1-Trichloro-2,2-bis (p-chlorophenyl) Ethane

Yukako OKAZAKI; Tomoyasu SETOGUCHI; Tetsuyuki KATAYAMA

doi:10.1271/bbb.60257

Food & Nutrition Science Notes

Effects of Dietary myo-Inositol, D-chiro-Inositol and L-chiro-Inositol on Hepatic Lipids with Reference to the Hepatic myo-Inositol Status in Rats Fed on 1,1,1-Trichloro-2,2-bis (p-chlorophenyl) Ethane

Yukako OKAZAKI, Tomoyasu SETOGUCHI, Tetsuyuki KATAYAMA

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Keywords: inositol stereoisomer, hepatic lipid, hepatic free myo-inositol level, phosphatidylinositol, 1,1,1-trichloro-2,2-bis (p-chlorophenyl) ethane (DDT)

JOURNAL FREE ACCESS

2006 Volume 70 Issue 11 Pages 2766-2770

DOI https://doi.org/10.1271/bbb.60257

View "Advance Publication" version (November 7, 2006).

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Abstract

The effects of dietary 0.2% inositol stereoisomers on the hepatic lipids and myo-inositol (MI) status in rats fed with 1,1,1-trichloro-2,2-bis (p-chlorophenyl) ethane (DDT) were investigated. Dietary MI reduced the hepatic lipids in the rats fed with DDT. Dietary D-chiro-inositol (DCI) and L-chiro-inositol (LCI) both had a promoting effect on the increase in hepatic lipids due to DDT feeding. Dietary MI enhanced the hepatic free MI level and the phosphatidylinositol/phosphatidylcholine ratio, but dietary DCI reduced the level and ratio.

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