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Bioscience, Biotechnology, and Biochemistry
Vol. 73 (2009) No. 8 P 1908-1910



Organic Chemistry Notes

Four compounds were isolated from scrap cultivation beds of the mushroom, Hericium erinaceum. Compounds 14 were identified as methyl 4-hydroxy-3-(3-methylbutanoyl) benzoate, 2-chloro-1,3-dimethoxy-5-methylbenzene, methyl 4-chloro-3,5-dimethoxybenzoate, and 4-chloro-3,5-dimethoxybenzaldehyde by an interpretation of the NMR and MS data, respectively. This is the first reported isolation of 1 from a natural source. All the compounds showed protective activity against endoplasmic reticulum stress-dependent cell death.

Copyright © 2009 by Japan Society for Bioscience, Biotechnology, and Agrochemistry

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