Alteration of Ethanol Tolerance Caused by the Deficiency in the Genes Associated with Histone Deacetylase Complex in Budding Yeast

Takao MATSUDA; Shuki FUJIMURA; Hiroshi SUDA; Yoshimi MATSUFUJI; Junichi NAKAGAWA

doi:10.1271/bbb.110232

Biochemistry & Molecular Biology Notes

Alteration of Ethanol Tolerance Caused by the Deficiency in the Genes Associated with Histone Deacetylase Complex in Budding Yeast

Takao MATSUDA, Shuki FUJIMURA, Hiroshi SUDA, Yoshimi MATSUFUJI, Junichi NAKAGAWA

著者情報

キーワード: Saccharomyces cerevisiae, epigenetic gene regulation, ethanol tolerance, stress response, histone deacetylase

ジャーナルフリー

2011 年 75 巻 9 号 p. 1829-1831

DOI https://doi.org/10.1271/bbb.110232

View "Advance Publication" version (September 7, 2011).

詳細

抄録

Upon exposure to 8% ethanol, survival and growth of yeast strains deficient in histone deacetylase complex genes was examined. Of the 18 mutants tested, the Δsir3 and Δsir4 strains showed higher resistance to ethanol, while the Δrco1, Δhos3, Δhda2, and Δhst1 strains were more sensitive than the wild type. Furthermore, these ethanol-resistant patterns varied under aerobic and anaerobic culture conditions.

責任著者(Corresponding author)

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