Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Food & Nutrition Science Notes
Influence of GABA on Brain Protein Synthesis Mediated by the Mammalian Target on the Rapamycin Pathway
Panicha THANAPREEDAWATMiho OHSUMIKazutoshi HAYASEFumiaki YOSHIZAWAHidehiko YOKOGOSHI
Author information
JOURNAL FREE ACCESS

2013 Volume 77 Issue 3 Pages 660-662

Details
Abstract

This study determined the influence of γ-aminobutyric acid (GABA) on brain protein synthesis via the mammalian target of rapamycin (mTOR) pathway. Experiments were carried out on three groups of 6-wk-old male rats with 0%, 0.5%, and 1% GABA. The percentage-phosphorylated S6K1 and growth hormone (GH) concentration was significantly increased by the GABA administration. The insulin level was not significantly changed, while the insulin-like growth factor 1 (IGF-1) level was significantly decreased by the GABA administration.

Content from these authors

This article cannot obtain the latest cited-by information.

© 2013 by Japan Society for Bioscience, Biotechnology, and Agrochemistry
Previous article Next article
feedback
Top