Agricultural and Biological Chemistry
Online ISSN : 1881-1280
Print ISSN : 0002-1369
ISSN-L : 0002-1369
Studies on Streptomycetes
Part II. Difference between Antibiotic No.45449-A (Zygomycin A) and other Antibiotics Belonging to the Neomycin Group
Motoo SHIBATAEiji HIGASHIDEToshihiko KANZAKIHiroichi YAMAMOTOKoiti NAKAZAWA
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ジャーナル フリー

1961 年 25 巻 3 号 p. 176-180

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Judging from its antibiotic spectrum and chemical properties, antibiotic No.45449-A was found to be an antibiotic belonging to the neomycin group.
This antibiotic was compared with other antibiotics belonging to the neomycin group by the following three methods.
First, comparison of the antibiotic spectrum of No.45449-A with those of neomycin, kanamycin hydroxymycin and paromomycin indicated that the former is different from the latter. Secondly, test for cross resistance using St. pulveraceus and St. fradiae as test microorganism showed that No.45445-A is distinguishable from neomycin and kanamycin. Thirdly, investigation of diffusion assay ratios by the method of Fischer et al. also presumed No.45449-A to be a new antibiotic differing from neomycin and kanamycin.
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