抄録
Mutants of Bacillus subtilis Marburg capable of synthesizing adenosine from adenine in high yield were described. The mutants of B. subtilis Marburg 160 (tryptophan-dependent, streptomycin-resistant) were isolated via either ultraviolet light irradiation or 2, 6-diaminopurine treatment. In experiments with 2, 6-diaminopurine, mutants were obtained in very high frequency. It was found that mutants with purine dependency besides tryptophan requirement and streptomycin resistance, accumulated large amounts of adenosine when grown in a glucose mineral medium containing large amounts of adenine. The parent strain and mutants with amino acids, thiamine or adenine dependency, on the other hand, accumulated only small amounts of adenosine and large amounts of hypoxanthine from adenine.
