5, 6-Dimethoxysterigmatocystin and Related Metabolites from Aspergillus multicolor

Abstract

From the mycelial mats of Aspergillus multicolor Sappa, five metabolites were isolated. Two of them were new metabolites; one was 5, 6-dimethoxysterigmatocystin (1) and the other 5, 6-dimethoxydihydrosterigmatocystin (4). The structure of 1 was determined by chemical degradation, NMR techniques of benzene-induced solvent shifts and X-ray structure analysis of its acetate (2). The three metabolites were identified as sterigmatocystin, averufin and versicolorin C, respectively.