Structures of Naphthoquinones Produced by the Fungus, Fusarium sp., and Their Biological Activity toward Pollen Germination

Abstract

From an unidentified Fusarium sp., eight substances possessing a 1, 4-naphthoquinone skeleton were isolated (F2-F9) and their structures were elucidated from the physical and chemical evidence. The effect of these compounds together with 1, 4-naphthoquinone, 5-hydroxy-1, 4-naphthoquinone and 5, 8-dihydroxy-1, 4-naphthoquinone on the pollen germination of Pinus thunbergii Parl was examined. 5, 8-Dihydroxy-1, 4-naphthoquinone showed marked inhibitory activity.