Enzymatic Production of Ribavirin from Orotidine by Erwinia carotovora AJ 2992
1988 年 52 巻 6 号 p. 1499-1504
詳細
1988 年 52 巻 6 号 p. 1499-1504
Microorganisms that produce ribavirin (1-β-D-ribofuranosyl-1, 2, 4-triazole-3-carboxamide; virazole®) directly from orotidine and 1, 2, 4-triazole-3-carboxamide (TCA) were screened from our stock cultures. Of the 425 strains, Erwinia carotovora AJ 2992 was found to possess potent ribavirin-producing ability, from orotidine and TCA. In the presence of intact cells of E. carotovora AJ 2992, 183 mM ribavirin was produced from 300 mM orotidine and 300 mM TCA on 48 hr reaction.
この記事は最新の被引用情報を取得できません。
