Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Stimulation of Insulin-dependent Glucose Transport and Lipogenesis in Isolated Rat Adipocytes by Trypsinized Soybean Glycinin Acidic Subunit A1a
Yuji IshikawaChino KumagaiRyuichi MoriyamaShio Makino
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JOURNAL FREE ACCESS

1994 Volume 58 Issue 3 Pages 590-591

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Abstract

Besides the stimulating effect of trypsinized soybean glycinin acidicsubunit A1a on insulin-mediated antilipolysis, the trypsinized A1a was found to enhance insulin-mediated glucose transport and lipogenesis in the presence of cAMP stimulators such as isoproterenol and 1-methyl-3-isobutylxanthine in isolated rat adipocytes. Furthermore, it was indicated that insulin and the cAMP stimulators, which generally exert counter-regulatory effects, act synerigistically on the in vitro lipogenesis.

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