Synthesis of (2S, 4R, 5S)-2, 4, 6-Trimethyl-5-heptanolide, a Sex Pheromone Component for Macrocentrus grandii

Abstract

(2S, 4R, 5S)-2, 4, 6-Trimethyl-5-heptanolide (1), a sex pheromone component for Macrocentrus grandii, was synthesized by starting from methyl (R)-citronellate (2) and employing bromolactonization (10→11)as the key reaction.